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Designs for Health Liposomal D3 50ml


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Liposomal Vitamin D3 50ml

  • 1000IU of Vitamin D3 per Spray
  • New innovative proprietary Liposomal Technology for optimal absorption and delivery
  • Maintains healthy immune system function
  • Provides support for healthy bones
  • Maintains muscle function
  • Soy, dairy and gluten-free
Vitamin D is a fat-soluble secosteroid hormone that can be found in three main forms – vitamin D (calcitriol), vitamin D2 (ergocalciferol), and vitamin D3 (colecalciferol). Calcitriol is endogenously produced in the body via ultraviolet B exposure to the epidermis.1 Ergocalciferol is the synthetic form of vitamin D and is most commonly added to food. Colecalciferol is synthesised in the skin from 7-dehydrocholesterol and is also found in a limited range of food sources such as shiitake mushrooms and oily fish. Vitamin D is required for a vast number of biological processes.
Due to a number of disease states having low vitamin D status in common, serum vitamin D as 25-hydroxyvitamin D (25(OH) D) is often routinely tested. Vitamin D supplementation is suggested in those with a clinical vitamin D deficiency. Variations in vitamin D status are heavily dependent upon a number of factors, including sex, season, location, age, health conditions, and lifestyle.

Liposomal technology

Liposomes are vesicles with phospholipid bilayers surrounding an aqueous or lipid solution. The phospholipid make-up of the bilayer allows for the liposomes to permeate the cell membrane and promote cell to cell fusion, resulting in delivery of the nutrients enclosed within the liposomes into the cells.
Liposomal technology enhances bioavailability and absorption.3 Efficient intracellular delivery is achieved via superior absorption of the smaller sized liposome particles. Liposomal delivery also allows for greater stability in the bloodstream and can be retained in the blood without degradation or oxidation.

Bone health

Vitamin D plays a primary role in maintaining bone health and integrity. Both bone mass and mineralisation require adequate vitamin D levels. Two of the main nutrients involved in strengthening the bone matrix, calcium and phosphorous, require adequate vitamin D in order to maintain homeostasis. Evidence suggests that as we age, vitamin D levels can decrease, leading to an imbalance in calcium and phosphorous.6 Hormonal factors also influence bone resorption and formation – therefore, vitamin D is both, directly and indirectly, responsible for processes involved in the mineralisation of the extracellular matrix in bone tissue.

Immune system

The immune system requires optimal vitamin D levels to function. A number of important immune cells have vitamin D receptors and vitamin D metabolising enzymes, including monocytes, B cells, T cells, and antigen-presenting cells.
Results from in vivo human and animal studies show numerous beneficial outcomes for immune function with vitamin D supplementation.8 Calcitriol has specifically been shown to enhance macrophage and monocyte antimicrobial activity, as well as enhancing innate immune cell chemotaxis and phagocytosis.8 Calcitriol is also involved in adaptive immunity where it directly influences B cell homeostasis, memory and plasma cell inhibition, and promotion of apoptosis of immunoglobulins responsible for producing B cells.

Maternal health and foetal development

Vitamin D has a vital role in foetal development due to its requirement in maintaining calcium homeostasis and supporting healthy bone growth. Young children and pregnant women are at particular risk of vitamin D deficiency, with numerous studies linking low serum 25(OH)D to poor health outcomes that can extend beyond bone health.9 Maternal 25(OH)D is believed to cross the human placenta to the foetus, as has been demonstrated in rat studies. The placenta possesses vitamin D receptors, as well as producing the enzyme CYP27B1 which is responsible for the conversion of 25(OH)D to the active form of vitamin D.
There is also a demonstrated connection between vitamin D, immune function, and maternal health. Adequate vitamin D levels support immune function, which may provide support for the appropriate maternal immune response to the placenta.

Directions for use:

Adults: Take 1 spray (285 microlitres) once daily by mouth, or as directed by your healthcare professional. Spray into the mouth under the tongue and hold in the mouth for 30 seconds before swallowing. Take on an empty stomach.


Liposomal Vitamin D3 (as Colecalciferol) Colecalciferol 25 micrograms
equiv. Vitamin D3 1000 IU


Contains 12% Ethanol. Store at 2-8 degrees, Refrigerate, do not freeze.