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Designs for Health LV-GB Complex 120Caps


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A unique formula aimed at maintaining the health and function of the liver whilst supporting bile production and secretion.
  • A unique formula aimed at maintaining the health and function of the liver and gall bladder.
  • Supports bile production and secretion.
  • Contains standardised extracts of both St. Mary’s Thistle and Globe Artichoke at therapeutic dose.
  • Also contains Schisandra chinensis, Rosmarinus officinalis, Beta vulgaris, Taurine and Inositol.
  • Contains calcium saccharate (calcium d-glucarate) as an excipient ingredient.
The liver is a complex and vital organ that makes up around 2% of our body weight and receives nutrient-rich blood from the stomach, intestines, pancreas and spleen via the portal vein and oxygenated blood from the aorta via the hepatic artery. It holds around 13% of the body’s total blood volume at any given time. It functions in a number of critical physiological processes, including detoxification, digestion, metabolism & energy production, immunity, macro and micronutrient storage and metabolism, endocrine signalling, lipid and cholesterol maintenance, glycogen production and storage, blood coagulation homeostasis, heme breakdown and the synthesis of bile, hormones, amino acids and other compounds vital for cellular functioning and the sustenance of life.

The most well-known function of the liver is that of detoxification, which occurs in three phases – two of them biochemical and one mechanical.
  • Phase one (functionalisation): The addition of a reactive oxygen group, such as a hydroxyl, carboxyl, or amino group, to form a reactive site on the toxic compound in readiness for phase two. The addition of this group can render the compound highly reactive and contribute to tissue damage and subsequent disease or adverse drug events if phase two doesn’t begin immediately or is dysfunctional.
  • Phase two (conjugation): The addition of a water-soluble group to the reactive site created in phase one. The water-soluble group can include glucuronic acid, sulfate, glutathione, amino acids, or an acetyl or methyl group. This increases the hydrophilicity, enabling it to be safely excreted via the bile or urine.
  • Phase three (elimination): Includes the excretion of the end product either via the bowel under the influence of peristalsis, healthy microbiota and adequate stool bulk or the kidneys (in urine)
A fine balance between phases one and two needs to be maintained as the metabolites produced during phase one can be more toxic and reactive than the starting compound. If phase two isn’t initiated immediately or is initiated poorly or dysfunctionally, tissue damage and disease can ensue.


Adults: Take 4 capsules daily with a large glass of water, or as directed by your healthcare professional.


Active Ingredients (per vegetarian hard capsule): Silybum marianum extract dry concentrate 131.25 mg From min dry fruit 10.5 g Standardised to 105 mg silymarin Standardised to 26.25 mg silybin Cynara scolymus extract dry concentrate 160 mg From min. dry leaf 480 mg Standardised to 8 mg caffeoylquinic acid calc. as cynarin Schisandra chinensis extract dry concentrate 30 mg From dry fruit 750 mg Rosmarinus officinalis extract dry concentrate 25 mg From dry leaf 500 mg Beta vulgaris extract dry concentrate 11.25 mg From dry root 112.5 mg Taurine 225 mg Inositol 125 mg


Do not use this product if you have a bile duct obstruction.