Metagenics NeuroCalm Soothe 30Caps

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To Relieve Symptoms Of Mild Anxiety And Support Emotional Wellbeing.

Clinical Benefits:

• Lavender and lemon balm are shown to be as effective as pharmaceuticals in reducing anxiety. A 2020 clinical trial involving 45 patients with low mood showed that the administration of lavender and lemon balm over 8 weeks were both equally as effective as a selective serotonin reuptake inhibitor (SSRI) in reducing feelings of anxiety, sexual dysfunction and decreased appetite.³ In further research, administration of 160 mg of lavender oil daily was superior in lowering the Hamilton Anxiety Rating Scale (HAMA) scores in comparison to placebo⁴ whereas 80 mg of lavender oil was observed to be as effective as an SSRI.
• Neural communication through action potentials and neurotransmitter signalling plays a significant role in anxiety and low mood. Increased glutamate and/or reduced GABA activity and an increased influx through the voltage gated calcium channels can lead to neuronal excitation in mild anxiety.^5,6 Lemon balm reduces neuronal excitation by helping to inhibit the degradation of GABA⁷ Lavender oil's anxiolytic and mood enhancing activity may be due to the modulation of serotonin and dopamine, as well as endocannabinoid activity and modulation of voltage gated calcium channels.⁸
• Helps to regulate autonomic and HPA axis overactivity, reducing physical symptoms of anxiety. 200 mg of theanine may address the sympathetic nervous system response to stress such as regulating heart rate variability, as well as modulating the cortisol response.⁹ Lemon balm has been shown to reduce heart palpitations.¹⁰
• Supports neuronal resilience to stress. Uncontrollable and prolonged stress reduces neurogenesis in the hipppocampus, associated with a depletion of brain derived neurotropic factor (BDNF), linked to low mood, anxiety and a dysfunctional stress response. Lavender oil may help to improve neuroplasticity¹¹ and lemon balm and theanine may help to modulate BDNF and neurogenesis.^{12, 13}
• 200 mg of theanine increases α-brain wave activity¹⁴, inducing mental relaxation as well as improving reaction time amongst anxiety subjects with mild anxiety compared to placebo.¹⁵
• NeuroCalm Soothe contains a low caffeine green tea extract, and AquaCelle^®, a self-emulsifying delivery system to improve the absorption of lipophilic ingredients.

Directions:

Adults: To calm the mind and support emotional wellbeing: Take one tablet twice daily with food.

In times of acute, mild anxiety: Take two capsules daily with food.

Ingredients:

Free from animal products, dairy protein, lactose, eggs, gluten, wheat, nuts, yeast and soy protein.